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schemes. The schedule of what is allowable and what is not under the indirect schemes is therefore of considerable interest to doctors. The established practice before telemedicine arrived on the scene was to reimburse doctors only for face-to-face consultations. That is now changing. Teleradiology is reimbursed nationally (Section 1.3.3) and Medicaid reimbursement for telemedical consultations is provided in Arkansas, Georgia, Montana and West Virginia. Non-videoconferencing applications such as remote cardiac and foetal monitoring. telepathology and teleradiology have been nationally reimbursed by Medicare, for some time [4]. From January 1999, Medicare reimbursement is also available for telemedicine services in rural counties (Section 5.2.2 and reference [315]). As noted, the US General Accounting Office found no evidence to support the Health Care Financing Administration s assertion that offering fee-forservice reimbursement of telemedicine services to Medicare patients would vastly increase expenditure in the USA [214]. Others [326] have questioned whether reimbursement is the big issue that it is made out to be, and further relaxation to allow controlled reimbursements seems likely.

feel for the concepts of mean and variance, before applying standard formulas for those quantities in the case of special distributions. 4. Theorem 2 gives * 6. We obtain 2xe

We don t want to force them to fix into a position they couldn t reverse later on, Armen explained Besides, he sensed a change in attitude at the FDA more of an insistence on going by the book tied in with the staff transfer However, the second trial, if it ran its full course, would cost the company $15 to $20 million and delay things an extra year and a half, to mid-2006 or even later As it turned out, once Gupta submitted the briefing material, the FDA wanted some additional information, and the meeting had to be put off two months until late July (Armen was right on the money in one of his predictions: the FDA did, indeed, ask for a third radiologist to assess trial results, as a tie-breaker.

Prepare to ignore industry borders. Be willing to take risks. Even when someone else seems to have locked up the market. Be willing to make mistakes. Big ones. If you passionately believe in an idea, pay no heed to the naysayers. It is their job to squelch the song and dance. Do not let them.

) In addition, the agency requested yet more background on the assays that Antigenics would be using to test the drug s potency; that was another 300-page submission On top of all that, virtually the entire FDA review staff changed yet again Even Phil Noguchi transferred to a different part of the agency So now about ten people from Antigenics regulatory and clinical staff were spending an hour or two per week on the phone and e-mail trying to bring the newcomers up to date, plus sending copies of material they had already submitted Armen guessed it would take the new FDA people a few months to catch up It was a heck of a maiden voyage for a company trying to cure cancer To be fair, it was also far from the norm.

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and 14. (s 2)2Y 2.1s Y 3.9 4 2.1. Hence 2.1s (s 4.5 2)2 2.1(s 2) (s 4.2 2)2 4.5 .

FDA staff have been gracious enough to admit, Armen told me with a wry smile, that this has not been an optimal way to deal with our situation At least the 90-minute July meeting went well, according to Armen in fact, the agency even asked Antigenics whether its method of electronic data collection could be used as an oncology standard Then it was on to the next step..

If you ve ever had to relocate a Web site from one directory to another, you know the laborious job of making sure all your references are intact. Dreamweaver takes some of the tedium out of this chore. When you use Save As from Dreamweaver, all of the file paths within HTML attributes, such as the image source files and links, are automatically updated. Dreamweaver extends the same functionality to URLs contained within behaviors. For example, suppose you have constructed a Web page that uses the Check Browser action to route users to various URLs, depending on the browser they are using. Should you elect to save your Web page in a different folder, for whatever reason, Dreamweaver automatically updates the referenced URLs. For this property to work correctly, a new function must be included in the behavior. The function, identifyBehaviorArguments(), passes the argument structure to Dreamweaver so it can update the URLs, if necessary. The function also identifies the layer objects in the behavior that Dreamweaver must correct if the Convert Layers to Tables command is used. The identifyBehaviorArguments() function accepts a string that contains the behavior function call, with arguments. The function then extracts the arguments into an array and identifies which arguments in the array are URLs, which ones are layer objects, and which ones are neither. Four identifying values are returned: URL: When the argument is a file or file path NS4.0ref: When the argument identifies a layer in Netscape syntax, such as