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Chitosan Chitin is an abundant, long, brous polymer of N-acetylglucosamine that is found in many invertebrates and is the chief component of fungal cell walls It is, for example, a major component of the shells of crustaceans such as crabs, lobsters and shrimps Chitin can be partly de-acetylated by treatment with sodium hydroxide to produce chitosan Chitosan has been available for about thirty years despite the current advertising claims of some suppliers that it is a new product that acts like a fat magnet and will revolutionise weight control The implication is that you can eat what you like and still lose weight with chitosan supplements The theory is that (fat and cholesterol) bind to ionised sites on the chitosan which prevents its digestion and absorption Claims of the fat-binding capacity of chitosan vary from four times its own weight to more than double this.

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taking has a fancy name: the task WBS The task WBS is nothing more than a top-down formulation of how project tasks t into the overall project structure It is an important planning tool because it serves as the basis of the project schedule The task WBS usually takes one of two possible forms: a table or a chart Let s say the project is to write a spy novel Exhibit 61 shows a tabular task WBS created for the project The hierarchy of tasks is plainly evident in this four-tier WBS At the highest level is the overall project: to write a spy novel At the next level down, there are four basic phases (for example, research background material, outline story) Each phase is broken down into tasks (for example, go to library), and each task is further broken down into subtasks (read up on US.

Such claims are not based upon in vivo studies but upon chemical laboratory experiments There is technical evidence that chitosan can bind fat and that large doses may increase the fat content of faeces in some animal studies Evidence that it has any signi cant effect upon faecal fat losses in humans is not apparent in the scienti c literature Gades and Stern (2003) evaluated the effect of chitosan (45 g/day spread over ve doses) on faecal fat content in 15 male subjects They concluded that the extra daily fat loss in faeces associated with this large dose of chitosan amounted to only 11 g/day (about 10 calories per day) This is a clinically insigni cant effect Guerciolini et al (2001) compared the effects of chitosan and a prescription drug, orlistat, upon faecal fat excretion using 12 adult subjects in a crossover study.

-Kazakhani relations) The number of levels needed for a WBS varies according to personal preference and project size Clearly, very large projects demand more levels than small projects Today s project scheduling software permits you to create WBSs with as many levels as you want Planners beware! Each time you add another level, you are increasing data entry and maintenance requirements dramatically, because a subtask typically has three to ve sub-subtasks hanging off it If you are not careful, you will create a WBS that will consume enormous amounts of administrative effort to maintain.

When trying to determine how many levels to add to the WBS, ask yourself: Do I really need to track my project at this level of detail On software development projects, for example, it often does not make sense to have WBSs with more than three layers, because the degree of uncertainty these projects experience is so great that it is not possible to collect and track reliable data at a ne level of detail Figure 62 shows a pictorial version of the WBS for the same project The WBS in this form looks something like an organization chart With this format, we can see at a glance the hierarchical relationships of the different pieces of the project Sometimes it is useful to include cost estimates for each subtask When we do this, we have something called a costed WBS.

To nd out the cost of a given level of the WBS, we add together the individual costs of the related items in the next level down We can estimate the cost for the total project by summing the costs of all the items at the lowest level of the WBS The lowest level is given the name work package level Such a process is called bottom-up cost estimating..